Collagen Nanoparticles
Collagen Nanoparticles
Collagen Nanoparticles | |
Product No | NRE-6009 |
CAS No. | 9007-34-5 |
Formula | Al2O34SiO2H2O |
APS | <100nm (Can be Customized) |
Purity | 99.9% |
Color | Light cream |
Molecular Weight | 202.185 g/mol |
Density | NA |
Melting Point | NA |
Boiling Point | NA |
Collagen Nanoparticles
Collagen is regarded as one of the most useful biomaterials. The excellent biocompatibility and safety due to its biological characteristics, such as biodegradability and weak antigenecity, made collagen the primary resource in medical applications. The main applications of collagen as drug delivery systems are collagen shields in ophthalmology, sponges for burns/wounds, mini-pellets and tablets for protein delivery, gel formulation in combination with liposomes for sustained drug delivery, as controlling material for transdermal delivery, and nanoparticles for gene delivery and basic matrices for cell culture systems. It was also used for tissue engineering including skin replacement, bone substitutes, and artificial blood vessels and valves.
collagen powders, collagen nanofibres can also contribute to skin wound healing. As collagen is an extremely pliable protein, it can be fabricated into various forms, one of which is nanofibres. One method through which collagen nanofibres can be fabricated is electrospinning. Electrospinning can result in aligned or random collagen nanofibres, both of which have different purposes in tissue engineering, as the fibre alignment can determine its mechanical properties and cellular activities. Electrospun collagen fibres are considered better compared to other polymer nanofibres due to collagen being present largely in the ECM. The structure of collagen nanofibres also highly resembles the natural structure of native tissues, with low immunogenicity and good biocompatibility.